TPS NEUROLITH ALZHEIMER
CERTIFIED ALZHEIMER'S THERAPY · CE-APPROVED MEDICAL DEVICE
Alzheimer's therapy with TPS Neurolith –
Gentle help at the Dr. Putz Center
An Alzheimer's diagnosis is a profound blow. Suddenly, questions arise for which no one has easy answers: What happens now? What can be done? Can Alzheimer's be stopped?
At the Inuspherese Center Dr. Putz, we complement standard medical therapy with a modern, gentle procedure: transcranial pulse stimulation (TPS) using the Neurolith® system from Storz Medical . No surgery, no anesthesia, no pain.
TPS IN THE VIDEO
What is transcranial pulse stimulation (TPS)?
Imagine being able to selectively stimulate specific brain regions – without surgery, without medication, simply from the outside, through the head. That's exactly what TPS therapy makes possible.
The Neurolith® device from the Swiss manufacturer Storz Medical generates very short, low-energy sound pulses (acoustic shock waves). These pulses penetrate up to eight centimeters deep into the brain and target precisely those regions that typically decline in Alzheimer's disease: areas responsible for memory, language, attention, and orientation.
The "active ingredient" of this method is not a chemical – it consists of physical impulses. Shockwave therapy has been used safely in medicine since 1980 (originally for breaking up kidney stones, but with significantly higher energy). In TPS, the pulses are dosed so that they do not damage the tissue, but rather activate it.
NEUROLITH® 3D navigation system for precise brain stimulation in Alzheimer's therapy
The camera-based BodyTrack® system visualizes the treated areas on a 3D model of the patient's head. © Storz Medical AG
How does TPS therapy affect the brain?
The gentle pulses trigger several natural processes in the brain:
Blood circulation in the treated areas is improved. More blood means more oxygen and more energy for the nerve cells.
New small blood vessels form – the brain is literally better supplied.
The body releases growth factors (BDNF, GDNF) – substances produced by the body that act like fertilizer for nerve cells: they help damaged cells to recover and form new connections.
Neuroplasticity is promoted – the brain's ability to reorganize itself and find new ways of doing things.
Mood can also improve because certain neurotransmitters become more balanced.
TPS attempts to counteract precisely where Alzheimer's disease begins – with lost connections and poorer blood circulation.
DEVICE
NEUROLITH® TPS system from Storz Medical with treatment software and real-time brain navigation
The NEUROLITH® system: The patient's MRI data and the position of the pulses are visualized on the screen in real time. © Storz Medical AG
The Neurolith® is currently the only system approved specifically for Alzheimer's treatment. During the session, the position of the pulses is tracked in real time on the screen using your own MRI scan – a camera-assisted BodyTrack® system navigates precisely through your personal brain. Learn more about the method from the development team at the Medical University of Vienna .
The camera-based BodyTrack® system visualizes the treated areas on a 3D model of the patient's head. © Storz Medical AG
DEVICE
Patient during TPS treatment with Neurolith at the Inuspherese Center Dr. Putz
During the TPS session, the physician precisely places the handpiece on the scalp. The recognition glasses enable precise navigation via the BodyTrack® system. © Storz Medical AG
During a session, you sit comfortably in a treatment chair – fully awake and responsive throughout. You will feel a light, rhythmic tapping on your head. Many patients describe it as pleasant. After 30 minutes, you go home.
This is how the TPS treatment works
Treatment protocol (according to clinical studies)
Step
What happens
Length of time
1. Initial consultation
Medical history, findings, indication assessment
approx. 60 min.
2. MRI scan
If none exist, assign externally (T1-weighted)
external
3rd treatment cycle
6 sessions of 30 minutes each, approx. 6,000 pulses/session targeting specifically selected brain areas
2 weeks
4. Refresher sessions
One session every 4–6 weeks to maintain the effect.
ongoing
5. Progress monitoring
Memory and attention tests, medical consultation
after 3, 6, 12 months
Transauricular vagus nerve stimulation (tVNS) via the ear
What vagus nerve stimulation does:
Anti-inflammatory effects: Studies show that controlling the autonomic nervous system can reduce inflammatory responses by up to 78%.
Regeneration in Long Covid & ME/CFS: Combating “brain fog” and massive exhaustion.
Stress reduction & mental balance: Significant results in anxiety disorders, panic attacks and depression.
Organ and circulatory support: Support for circulatory disorders, lymphedema, and to accelerate wound healing.
Long Covid Syndrom
Autoimmune diseases in which misguided immune responses are present
Chronic inflammations as well as so-called silent inflammations
Inflammatory bowel diseases such as ulcerative colitis or Crohn's disease)
multiple sclerosis
Neurologically degenerative diseases such as Alzheimer's disease or Parkinson's disease
Heavy metal contamination
Long Covid Syndrom
Autoimmune diseases in which misguided immune responses are present
Chronic inflammations as well as so-called silent inflammations
Inflammatory bowel diseases such as ulcerative colitis or Crohn's disease)
multiple sclerosis
Neurologically degenerative diseases such as Alzheimer's disease or Parkinson's disease
Heavy metal contamination
Long Covid Syndrom
Autoimmune diseases in which misguided immune responses are present
Chronic inflammations as well as so-called silent inflammations
Inflammatory bowel diseases such as ulcerative colitis or Crohn's disease)
multiple sclerosis
Neurologically degenerative diseases such as Alzheimer's disease or Parkinson's disease
Heavy metal contamination
Type of therapy
Gentle sound pulses
antibody drug
administration
Non-invasive, without medication
Infusion via the vein
Treatment frequency
6 sessions every 2 weeks, then a refresher course
Every 2–4 weeks, for approximately 1.5 years
Operating principle
Blood flow, growth factors, neuroplasticity
Dissolution of beta-amyloid plaques
MRI scan required
Follow-up examinations after 3, 6, and 12 months
Regular MRI scans due to possible cerebral edema
cost bearer
Self-payer
Currently, specialized centers; reimbursement on a case-by-case basis.
These two therapies are not mutually exclusive – they can even complement each other. We will discuss which combination is best for you with your treating specialist. You can also find an overview of the new antibody therapies at the Austrian Alzheimer Society .
For whom is Alzheimer's therapy with TPS suitable?
TPS treatment is intended for people with mild to moderate Alzheimer's dementia . The earlier the diagnosis, the better the conditions – because then there is still sufficient functional brain tissue available to be stimulated.
According to the manufacturer, this treatment is not suitable for:
metal parts or implants in the head area
Pacemakers (that are not approved for focused shockwave therapy)
Malignant tumor in the treatment area
Thrombosis in the treatment area
Untreated blood clotting disorders (e.g., hemophilia)
pregnancy
Cortisone treatment within the last six weeks before the first session
Simultaneous use of medications that lower the seizure threshold
Special caution
Individual medical assessment is necessary: benign tumor in the treatment area, skull bone defects.
Whether TPS is suitable for you personally will be clarified in a detailed initial medical consultation – in a relaxed and respectful manner.
Correctly detecting Alzheimer's disease – modern diagnostics from blood
Effective treatment requires a reliable diagnosis. We rely on two modern markers:
A protein fragment that increases early in Alzheimer's disease. Suitable for the early detection or exclusion of Alzheimer's disease.
The first officially approved blood test for Alzheimer's disease in Europe. It measures the ratio of two proteins, which is already altered at a very early stage.
Both tests are useful if you or a relative notice changes – word-finding problems, forgetfulness, disorientation – and are seeking clarity.
NAD+ infusion – energy for your cells
NAD+ (nicotinamide adenine dinucleotide) is a naturally occurring fuel found in every cell – essential for energy production, repair processes, and protection against oxidative stress. NAD+ levels decrease with age and in cases of chronic illness. NAD+ appears to play a particularly important role in Alzheimer's disease.
At the Dr. Putz Center, we administer NAD+ as an intravenous infusion. This allows the active ingredient to enter the bloodstream directly. NAD+ is not an Alzheimer's therapy in itself – it is a supportive measure that we use specifically to complement TPS therapy when appropriate in individual cases.
Our holistic concept – nothing works in isolation
However effective modern methods may be, a single method is not enough for a complex disease like Alzheimer's. Therefore, we combine several components into a coherent treatment plan:
Blood tests (pTau181, Aß42/40), MRI, medical consultation
as a core procedure in the Alzheimer's indication
with tDCS (gentle direct current stimulation) and taVNS (vagus nerve stimulation at the ear) – specifically for accompanying symptoms
e.g. with NAD+ infusions, B vitamins, individual optimization
We do not promise a cure. We promise care, time, and a concept developed according to current scientific standards.
→ More about our complete neuromodulation services: Neuromodulation overview page
About Dr. Carmen Putz
Dr. Carmen Putz, physician at the Inuspherese Center – specialist in neuromodulation and Alzheimer's therapy
Dr. Carmen Putz is a general practitioner with specialist training in anesthesiology and intensive care medicine. In private practice since 2009, she expanded her practice to include INUSpherese® in 2023.
Her areas of expertise include: environmental medicine, neurological diseases, Long-COVID/ME-CFS, and neuromodulation.
Location:
Hainburg an der Donau (near Vienna and Bratislava)
Can Alzheimer's disease be stopped? What studies on TPS show
The method was significantly co-developed at the Medical University of Vienna by the research group of Prof. Roland Beisteiner. Several studies indicate its effectiveness.
First clinical study. Patients showed measurable improvements in memory and attention tests after TPS, which remained stable over three months.
There is evidence that the typical brain tissue loss progresses more slowly after TPS.
Confirmation of the cognitive effects and additional evidence of an improvement in depressive symptoms.
Practical data on mild to severe Alzheimer's dementia.
These studies are promising and the reason why we are incorporating TPS into our treatment concept. TPS therapy is not a replacement for standard medically prescribed therapy – but rather a complementary method within our overall approach.
FAQ
Sources & further information
Studies on TPS:
Beisteiner R. et al. Transcranial Pulse Stimulation with Ultrasound in Alzheimer's Disease. Advanced Science, 2020. Full text
Popescu T. et al. Transcranial ultrasound pulse stimulation reduces cortical atrophy in Alzheimer's patients. Alzheimer's & Dementia: Translational Research, 2021. Full text
Matt E et al. Transcranial pulse stimulation (TPS) improves depression in AD patients. Journal of Translational Medicine, 2022. Full text
Cont C et al. Retrospective real-world pilot data on transcranial pulse stimulation in mild to severe Alzheimer's patients. Frontiers in Neurology, 2022. Full text
Manufacturers & Research:
Storz Medical – Neurolith® · Prof. Beisteiner / MedUni Vienna · Austrian Alzheimer Society
